Searchable abstracts of presentations at key conferences in endocrinology

ea0034oc2.2 | Endocrine regulation of cell behaviour | SFEBES2014

Inhibition of human NET cell proliferation by a peptide identified through phage display screening

Stevenson Mark , Lines Kate , Zalmas Lykourgos-Panagiotis , Javid Mahsa , Galvanovskis Juris , Grozinsky-Glasberg Simona , Wood Matthew , Grossman Ashley , Thakker Rajesh

Neuroendocrine tumours (NETs) occur in multiple sites including, the pancreas, gastrointestinal tract, lung, thymus, parathyroid, adrenals and pituitary. Current treatments for advanced NETs such as surgery, chemotherapy or radiotherapy, rarely achieve a cure due to metastases at presentation therefore additional therapeutic treatments are required. Identification of cell surface receptors or binding sites that are unique or up-regulated on tumour or neuroendocrine tissue coul...